KU-0060648 [881375-00-4]

MedChem Express

KU-0060648 [881375-00-4]

10

881375-00-4

Research Use Only

99.62

C33H34N4O4S

582.71

KU-0060648 is a dual inhibitor of PI3K and DNA-PK with IC50s of 4 nM, 0.5 nM, 0.1 nM, 0.594 nM and 8.6 nM for PI3Kalpha, PI3Kbeta, PI3Kgamma, PI3Kdelta and DNA-PK, respectively[1].

O=C(NC1=C(C2=CC=CC=C2S3)C3=C(C4=C5C(C(C=C(N6CCOCC6)O5)=O)=CC=C4)C=C1)CN7CCN(CC)CC7

-20°C, 3 years; 4°C, 2 years (Powder)

12352200