Kushenol K [101236-49-1]

MedChem Express

Kushenol K [101236-49-1]

10

101236-49-1

Research Use Only

C26H32O8

472.53

Kushenol K, a flavonoid antioxidant isolated from the roots of Sophora flavescens. Kushenol K is a cytochrome P-450 3A4 (CYP3A4) inhibitor with a Ki value of 1.35 microM[1]. Kushenol K shows weak antiviral activity against HSV-2 (EC50 of 147 microM)[2]. Kushenol K also inhibits the activity of SGLT1 and SGLT2[3].

COC(C=C1O)=C(C2=O)C(O[C@H](C(C=CC(O)=C3)=C3O)[C@@H]2O)=C1C[C@H](C(C)=C)CCC(C)(O)C

12352200