KV2 channel inhibitor-1

MedChem Express

KV2 channel inhibitor-1 [689297-68-5]

10

689297-68-5

Research Use Only

98.46

C20H17ClN4OS

396.89

KV2 channel inhibitor-1 is a selective K V 2 channel inhibitor with IC 50 s of 0.2 microM and 0.41 microM for K V 2.1 and K V 2.2, respectively. KV2 channel inhibitor-1 possesses good selectivity over K V 1.2 (IC 50 >10 microM). KV2 channel inhibitor-1 is >10-fold selective over Na V channels and other K V channels and displays weak activity on Ca V channels [1] .

O=C(NC1=CC=C2N=C(C3=CSC=N3)NC2=C1)CC(C)C4=CC=CC(Cl)=C4

-20°C,2°C to 8°C

12352200