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KY02111

M2800
AbMole BioScience
CAS Number1118807-13-8
DownloadDatasheet
Product group Chemicals
Estimated Purity>98%
Molecular Weight376.86
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    KY02111
  • Delivery Days Customer
    9
  • CAS Number
    1118807-13-8
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Molecular Formula
    C18H17ClN2O3S
  • Molecular Weight
    376.86
  • Scientific Description
    KY02111 is a widely used small molecule that boosts cardiomyogenesis. Chemical genetics of KY02111 identified squalene synthase (SQS) as a molecular target of KY02111. By disrupting the interaction of SQS with cardiac ER-membrane protein TMEM43, KY02111 impairs TGFbèta/SMAD signaling and recapitulates the clinical mutation of TMEM43 that causes an inherited heart disease.
  • SMILES
    COC1=CC=C(CCC(=O)NC2=NC3=CC=C(Cl)C=C3S2)C=C1OC
  • UNSPSC
    12352200

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References
TargetMol Chemicals
KY02111 [1118807-13-8]T2052
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