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KY19382 [2226664-93-1]

KY19382 [2226664-93-1]

T9025
TargetMol Chemicals
CAS Number2226664-93-1
DownloadMSDS
Product group Chemicals
Estimated Purity98.06%
Molecular Weight360.19
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    KY19382 [2226664-93-1]
  • Delivery Days Customer
    4
  • CAS Number
    2226664-93-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    KY19382
  • Estimated Purity
    98.06%
  • Molecular Formula
    C17H11Cl2N3O2
  • Molecular Weight
    360.19
  • Scientific Description
    KY19382 (2H-Indol-2-one, 5,6-dichloro-3-[1,3-dihydro-3-(methoxyimino)-2H-indol-2-ylidene]-1,3-dihydro-Ky19382) is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3beta( IC50s of 19 and 10 nM, respectively). It activates Wnt/beta-catenin signaling through inhibitory effects on both CXXC5-DVL interaction and GSK3beta activity. KY19382 can be used for the research of high fat diet (HFD) induced metabolic diseases.
  • Shelf life instruction
    3 years
  • SMILES
    CO\N=C1/C(/Nc2ccccc/12)=C1/C(=O)Nc2cc(Cl)c(Cl)cc12
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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