KYL peptide [676657-00-4]

TargetMol Chemicals

KYL peptide [676657-00-4]

9

Research Use Only

KYL peptide is an EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 microM); inhibits EphA4-EphrinA5 interactions (IC50 = 6.34 microM). Prevents AbetaO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. Exhibits a long half life in cell culture media (8 and 12 hours in PC3 and C2C12 media respectively). Neuroprotective.

-20°C

12352202