L-161982

MedChem Express

L-161982 [147776-06-5]

10

147776-06-5

Research Use Only

99.30

C32H29F3N4O4S2

654.72

L-161982 is a selective EP4 receptor antagonist. L-161982 completely blocks PGE2-induced ERK phosphorylation and cell proliferation of HCA-7 cells. L-161982 alleviates collagen-induced arthritis in mice[1][2].

O=C(C1=C(C)C=CS1)NS(=O)(C2=CC=CC=C2C3=CC=C(CN4C(CCCC)=NN(C5=CC=CC=C5C(F)(F)F)C4=O)C=C3)=O

-20°C,2°C to 8°C

12352200