L-364,373 [103342-82-1]

MedChem Express

L-364,373 [103342-82-1]

10

103342-82-1

Research Use Only

99.67

C25H20FN3O

397.44

L-364,373 (R-L3) is a voltage-gated Kv7.1 (KCNQ1)/mink channels activator. L-364,373 activates Iks (slow delayed rectifier potassium current) and shortens action potential duration in guinea pig cardiac myocytes, and suppresses early afterdepolarizations in rabbit ventricular myocytes[1].

O=C1N(C)C2=CC=CC=C2C(C3=CC=CC=C3F)=N[C@@H]1CC4=CNC5=C4C=CC=C5

-20°C,2°C to 8°C

12352200