L-372662 [162045-26-3]

MedChem Express

L-372662 [162045-26-3]

10

162045-26-3

Research Use Only

99.24

C33H38N4O6

586.68

L-372662 is a potent and orally active non-peptide oxytocin antagonist with a Ki value of 4.8. The Kd value of L-372662 for wild-type hOTR and [A318G]OTR is 5.8 nM and 73 nM. L-372662 shows selectivity to OTR:V1aR[1][2].

O=C(OC1)N(C2CCN(C(C3=C(OC)C=C(OC4CCN(CC5=C(C)[N+]([O-])=CC=C5)CC4)C=C3)=O)CC2)C6=C1C=CC=C6

-20°C,2°C to 8°C

12131703