l-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-lHpyrazolo [3,4-d]pyrimidin-l-yl]-l-piperidinyl]-2-propyn-l-one

BPS Bioscience

l-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-lHpyrazolo [3,4-d]pyrimidin-l-yl]-l-piperidinyl]-2-propyn-l-one

7

Research Use Only

C25H22N6O2

438.5 Da

l-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-lHpyrazolo[3,4-d]pyrimidin-l-yl]-l-piperidinyl]-2-propyn-l-one, is a derivative of the first-in-class covalent BTK inhibitor ibrutinib. Ibrutinib inhibits B-cell proliferation and survival by irreversibly binding the protein Brutons tyrosine kinase (BTK). B cell cancers are directly affected by this since the B-cell receptor pathway is often aberrantly active.

-20°C

12352200