L-745870 (hydrochloride) (Standard) [1173023-36-3]

MedChem Express

L-745870 (hydrochloride) (Standard) [1173023-36-3]

999

Research Use Only

L-745870 (hydrochloride) (Standard) is the analytical standard of L-745870 (hydrochloride). This product is intended for research and analytical applications. L-745870 hydrochloride is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 hydrochloride shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites and alpha-adrenoceptors[1][2][3].

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