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L-750667 (triHydrochloride) [1021868-80-3]

HY-114539
MedChem Express
CAS Number1021868-80-3
Product group Chemicals
Estimated Purity99.39
Molecular Weight527.66
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Overview

  • Supplier
    MedChem Express
  • Product Name
    L-750667 (triHydrochloride) [1021868-80-3]
  • Delivery Days Customer
    9
  • CAS Number
    1021868-80-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.39
  • Molecular Formula
    C18H22Cl3IN4
  • Molecular Weight
    527.66
  • Scientific Description
    L-750667 triHydrochloride is a selective antagonist for the D4 dopamine receptor, with a Ki value of 0.51 nM. The radiolabeled form of L-750667, [125I]L-750,667, has a Kd value of 0.16 nM for the D4 receptor. L-750667 triHydrochloride can reverse dopamine-induced inhibition of cAMP accumulation. It can be used to study the distribution and function of D4 dopamine receptors in the central nervous system and has potential applications in the fields of neuroscience and psychiatry[1][2].
  • SMILES
    IC1=CC=C(C=C1)N2CCN(CC2)CC3=CNC4=NC=CC=C43.[H]Cl.[H]Cl.[H]Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200