L-760735 [188923-01-5]

MedChem Express

L-760735 [188923-01-5]

10

188923-01-5

Research Use Only

99.0

C26H29ClF7N5O2

611.98

L-760735 is a high affinity, selective and orally active NK1 receptor antagonist with an IC50 of 0.19 nM for human NK1 receptors. L-760735 exhibits anxiolytic and antidepressant-like effects[1].

C[C@H](C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)O[C@@H](OCC2)[C@@](C3=CC=C(C=C3)F)([H])N2CC4=C(N=NN4)CN(C)C.Cl

-20°C

12352200