L-Asparagine (monohydrate) [5794-13-8]
HY-W017443
CAS Number5794-13-8
Product group Chemicals
Estimated Purity99.77
Molecular Weight150.13
Overview
- SupplierMedChem Express
- Product NameL-Asparagine (monohydrate) [5794-13-8]
- Delivery Days Customer10
- CAS Number5794-13-8
- CertificationResearch Use Only
- Estimated Purity99.77
- Molecular FormulaC4H10N2O4
- Molecular Weight150.13
- Scientific DescriptionL-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia[1][2][3][4][5].
- SMILESN[C@H](C(O)=O)CC(N)=O.[H]O[H]
- Storage InstructionRT
- UNSPSC12352200
![L(+)-Asparagine monohydrate [5794-13-8]](https://www.targetmol.com/group3/M00/03/74/CgoaEWY7TE-ELh1CAAAAAKNdpqU561.png)