L-Azetidine-2-carboxylic acid

MedChem Express

L-Azetidine-2-carboxylic acid [2133-34-8]

10

2133-34-8

Research Use Only

99.78

C4H7NO2

101.10

L-Azetidine-2-carboxylic acid is a proline analog. L-Azetidine-2-carboxylic acid upregulates the lipid autophagy marker LC3-II via activation of the PERK pathway. L-Azetidine-2-carboxylic acid increases pro-apoptotic BAX protein. L-Azetidine-2-carboxylic acid induces ATF6 cleavage and upregulates phosphorylated eIF2alpha levels. L-Azetidine-2-carboxylic acid induces ER stress, inducing protein misfolding and aggregation. L-Azetidine-2-carboxylic acid shows teratogenic, pro-inflammatory and pro-apoptotic effects [1] [2] [3] [4] [5] [6] [7] [8] [9] .

O=C([C@H]1NCC1)O

2°C to 8°C

12352200