L-Buthionine-(S,R)-sulfoximine

MedChem Express

L-Buthionine-(S,R)-sulfoximine [83730-53-4]

10

83730-53-4

Research Use Only

99.35

C8H18N2O3S

222.31

L-Buthionine-(S,R)-sulfoximine is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC 50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 microM, 8.6 microM, and 29 microM, respectively.

N[C@H](C(O)=O)CCS(CCCC)(=O)=N

-20°C

12352200