L-Plastin antibody [C1C3]
GTX114524
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetLCP1
Overview
- SupplierGeneTex
- Product NameL-Plastin antibody [C1C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.4 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID3936
- Target nameLCP1
- Target descriptionlymphocyte cytosolic protein 1
- Target synonymsbA139H14.1 (lymphocyte cytosolic protein 1 (L-plastin)); CP64; epididymis secretory protein Li 37; HEL-S-37; LC64P; LCP-1; LPL; L-PLASTIN; L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P); Lymphocyte cytosolic protein-1 (plasmin); plastin-2; PLS2
- HostRabbit
- IsotypeIgG
- Protein IDP13796
- Protein NamePlastin-2
- Scientific DescriptionPlastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- LCP1 preferentially binds clasped alphaMbeta2 integrin and attenuates leukocyte adhesion under flow. Tseng HY et al., 2018 Nov 21, J Cell SciRead more