Bio-Connect

L-Plastin antibody [C1C3]

Research Use Only
GTX114524
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetLCP1
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    L-Plastin antibody [C1C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.4 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID3936
  • Target name
    LCP1
  • Target description
    lymphocyte cytosolic protein 1
  • Target synonyms
    bA139H14.1 (lymphocyte cytosolic protein 1 (L-plastin)); CP64; epididymis secretory protein Li 37; HEL-S-37; LC64P; LCP-1; LPL; L-PLASTIN; L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P); Lymphocyte cytosolic protein-1 (plasmin); plastin-2; PLS2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP13796
  • Protein Name
    Plastin-2
  • Scientific Description
    Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • LCP1 preferentially binds clasped alphaMbeta2 integrin and attenuates leukocyte adhesion under flow. Tseng HY et al., 2018 Nov 21, J Cell Sci
    Read more