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WB analysis of various sample lysates using GTX32695 L2HGDH antibody. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of various sample lysates using GTX32695 L2HGDH antibody. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of various sample lysates using GTX32695 L2HGDH antibody. Dilution : 1:1000 Loading : 25microg per lane

L2HGDH antibody

GTX32695
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetL2HGDH
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Overview

  • Supplier
    GeneTex
  • Product Name
    L2HGDH antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500 - 1:2000. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID79944
  • Target name
    L2HGDH
  • Target description
    L-2-hydroxyglutarate dehydrogenase
  • Target synonyms
    C14orf160, L2HGA, L-2-hydroxyglutarate dehydrogenase, mitochondrial, 2-hydroxyglutarate dehydrogenase, L-alpha-hydroxyglutarate dehydrogenase, alpha-hydroxyglutarate oxidoreductase, alpha-ketoglutarate reductase, duranin
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9H9P8
  • Protein Name
    L-2-hydroxyglutarate dehydrogenase, mitochondrial
  • Scientific Description
    This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe cognitive disability. [provided by RefSeq, Jul 2008]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Brinkley G, Nam H, Shim E, et al. Teleological role of L-2-hydroxyglutarate dehydrogenase in the kidney. Dis Model Mech. 2020,13(11). doi: 10.1242/dmm.045898
    Read this paper
  • Shelar S, Shim EH, Brinkley GJ, et al. Biochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer. Clin Cancer Res. 2018,24(24):6433-6446. doi: 10.1158/1078-0432.CCR-18-1727
    Read this paper