
WB analysis of various sample lysates using GTX32695 L2HGDH antibody. Dilution : 1:1000 Loading : 25microg per lane
L2HGDH antibody
GTX32695
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetL2HGDH
Overview
- SupplierGeneTex
- Product NameL2HGDH antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:2000. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID79944
- Target nameL2HGDH
- Target descriptionL-2-hydroxyglutarate dehydrogenase
- Target synonymsC14orf160, L2HGA, L-2-hydroxyglutarate dehydrogenase, mitochondrial, 2-hydroxyglutarate dehydrogenase, L-alpha-hydroxyglutarate dehydrogenase, alpha-hydroxyglutarate oxidoreductase, alpha-ketoglutarate reductase, duranin
- HostRabbit
- IsotypeIgG
- Protein IDQ9H9P8
- Protein NameL-2-hydroxyglutarate dehydrogenase, mitochondrial
- Scientific DescriptionThis gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe cognitive disability. [provided by RefSeq, Jul 2008]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Brinkley G, Nam H, Shim E, et al. Teleological role of L-2-hydroxyglutarate dehydrogenase in the kidney. Dis Model Mech. 2020,13(11). doi: 10.1242/dmm.045898Read this paper
- Shelar S, Shim EH, Brinkley GJ, et al. Biochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer. Clin Cancer Res. 2018,24(24):6433-6446. doi: 10.1158/1078-0432.CCR-18-1727Read this paper





