Lactoferrin, Milk [146897-68-9]
16-13-120103
Protein IDP02788
Product group Proteins / Signaling Molecules
Overview
- SupplierAthens Research
- Product NameLactoferrin, Milk [146897-68-9]
- Delivery Days Customer9
- Applications SupplierIron Transport, Antimicrobial, Inflammation, Immunology
- CAS Number146897-68-9
- CertificationResearch Use Only
- Estimated Purity≥95% by SDS-PAGE
- Protein IDP02788
- Protein NameLactotransferrin
- Scientific DescriptionLactoferrin is a multifunctional glycoprotein abundantly present in milk, especially in colostrum, and plays a crucial role in the innate immune defense of breastfed infants. It exerts potent bacteriostatic and bactericidal effects in the intestinal tract by binding free iron, depriving pathogenic bacteria of this essential nutrient and thereby inhibiting their growth. Working synergistically with secretory IgA, lactoferrin helps protect the newborn’s gut from infections and supports the development of a healthy microbiome. In addition to its antimicrobial activity, lactoferrin acts as an iron-binding protein that facilitates the efficient absorption of dietary iron, contributing to the high bioavailability of iron in breast milk and reducing the risk of iron deficiency in infants. Beyond infancy, lactoferrin is being explored for therapeutic applications in treating infections, inflammatory bowel diseases, and iron metabolism disorders, as well as in functional foods and supplements to enhance immune function and support overall health.
- Shelf life instructionmore then 1 year
- SourcePrepared from human milk shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests.
- Storage Instruction-20C
- UNSPSC12352202
References
- Zhao, K. W., et al., (2019), 'HK2 Proximal Tubule Epithelial Cells Synthesize and Secrete Plasma Proteins Predominantly Through the Apical Surface', J Cell Biochem. 118(4): pp 924-933.Read this paper