Laduviglusib (monohydrochloride)
HY-10182A
CAS Number1797989-42-4
Product group Chemicals
Estimated Purity99.93
Molecular Weight501.80
Overview
- SupplierMedChem Express
- Product NameLaduviglusib (monohydrochloride) [1797989-42-4]
- Delivery Days Customer10
- CAS Number1797989-42-4
- CertificationResearch Use Only
- Estimated Purity99.93
- Molecular FormulaC22H19Cl3N8
- Molecular Weight501.80
- Scientific DescriptionLaduviglusib (CHIR-99021) monohydrochloride is a potent and selective GSK-3alpha/beta inhibitor with IC 50 s of 10 nM and 6.7 nM. Laduviglusib monohydrochloride shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib monohydrochloride is also a potent Wnt/beta-catenin signaling pathway activator. Laduviglusib monohydrochloride enhances mouse and human embryonic stem cells self-renewal. Laduviglusib monohydrochloride induces autophagy [1] [2] [3] .
- SMILESN#CC1=CC=C(NCCNC2=NC=C(C3=NC=C(C)N3)C(C4=CC=C(Cl)C=C4Cl)=N2)N=C1.[H]Cl
- Storage Instruction2°C to 8°C
- UNSPSC12352200