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Laflunimus [147076-36-6]

Laflunimus [147076-36-6]

Research Use Only
T11813
TargetMol Chemicals
CAS Number147076-36-6
DownloadMSDS
Product group Chemicals
Molecular Weight310.27
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Laflunimus [147076-36-6]
  • Delivery Days Customer
    72
  • CAS Number
    147076-36-6
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Laflunimus
  • Molecular Formula
    C15H13F3N2O2
  • Molecular Weight
    310.27
  • Scientific Description
    Laflunimus suppresses immunoglobulin (Ig) secretion, with IC50 values of 2.5 and 2 microM for IgM and IgG, respectively. Laflunimus also is a prostaglandin endoperoxide H synthase (PGHS) -1 and -2 inhibitor. Laflunimus is an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus is an orally active inhibitor of dihydroorotate dehydrogenase (DHODH).
  • Shelf life instruction
    3 years
  • SMILES
    Cc1cc(NC(=O)C(\C#N)=C(/O)C2CC2)ccc1C(F)(F)F
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200