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ProductsBack/Laflunimus (Standard) [147076-36-6]

Laflunimus (Standard) [147076-36-6]

HY-101813R
MedChem Express
CAS Number147076-36-6
Product group Chemicals
Molecular Weight310.27
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Laflunimus (Standard) [147076-36-6]
  • Delivery Days Customer
    5
  • CAS Number
    147076-36-6
  • Category Supplier
    CHEMICAL,detergents_surfactants
  • Certification
    Research Use Only
  • Molecular Weight
    310.27
  • Scientific Description
    Laflunimus (Standard) is the analytical standard of Laflunimus. This product is intended for research and analytical applications. Laflunimus (HR325) is an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus is an orally active inhibitor of dihydroorotate dehydrogenase (DHODH). Laflunimus suppresses immunoglobulin (Ig) secretion, with IC50 values of 2.5 and 2 microM for IgM and IgG, respectively. Laflunimus also is a prostaglandin endoperoxide H synthase (PGHS) -1 and -2 inhibitor[1][2].
  • SMILES
    O=C(NC1=CC=C(C(F)(F)F)C(C)=C1)/C(C#N)=C(C2CC2)\O
  • UNSPSC
    12352005

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