Protein structure of laminin-511
![ELISA anaiysis of seven recombinant human laminins using GTX17688 Laminin 511 antibody [12D].](https://www.genetex.com/upload/website/prouct_img/normal/GTX17688/GTX17688_20190522_ELISA_w_23060620_753.webp "ELISA anaiysis of seven recombinant human laminins using GTX17688 Laminin 511 antibody [12D].")
![IHC-Fr analysis of non-invasive breast carcinoma tissue using GTX17688 Laminin 511 antibody [12D]. Image A : Vascular basement membrane Image B : Mammary gland basement membrane Image C : Basement membrane-like structures surrounding tumor cells](https://www.genetex.com/upload/website/prouct_img/normal/GTX17688/GTX17688_20190522_IHC-Fr_1_w_23060620_598.webp "IHC-Fr analysis of non-invasive breast carcinoma tissue using GTX17688 Laminin 511 antibody [12D]. Image A : Vascular basement membrane Image B : Mammary gland basement membrane Image C : Basement membrane-like structures surrounding tumor cells")
![IHC-Fr analysis of lung cancer (SCC and ADC) tissue using GTX17688 Laminin 511 antibody [12D]. Left panel : Lung squamous cell carcinoma (SCC) Right panel : lung adenocarcinoma (ADC)](https://www.genetex.com/upload/website/prouct_img/normal/GTX17688/GTX17688_20190522_IHC-Fr_2_w_23060620_241.webp "IHC-Fr analysis of lung cancer (SCC and ADC) tissue using GTX17688 Laminin 511 antibody [12D]. Left panel : Lung squamous cell carcinoma (SCC) Right panel : lung adenocarcinoma (ADC)")
![IHC-Fr analysis of normal mammary gland using GTX17688 Laminin 511 antibody [12D]. Black arrows : Vascular basement membrane White arrowheads : Mammary gland basement membrane](https://www.genetex.com/upload/website/prouct_img/normal/GTX17688/GTX17688_20190522_IHC-Fr_w_23060620_810.webp "IHC-Fr analysis of normal mammary gland using GTX17688 Laminin 511 antibody [12D]. Black arrows : Vascular basement membrane White arrowheads : Mammary gland basement membrane")
![WB analysis of recombinant human intact laminin-511 (Lm511, containing consisting of alpha5, beta 1 and gamma 1 chains ) protein under non-reducing conditions using GTX17688 Laminin 511 antibody [12D]. Dilution : 1:1000](https://www.genetex.com/upload/website/prouct_img/normal/GTX17688/GTX17688_20190522_WB_w_23060620_520.webp "WB analysis of recombinant human intact laminin-511 (Lm511, containing consisting of alpha5, beta 1 and gamma 1 chains ) protein under non-reducing conditions using GTX17688 Laminin 511 antibody [12D]. Dilution : 1:1000")
Protein structure of laminin-511
Laminin 511 antibody [12D]
GTX17688
ApplicationsImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Purification/Extraction/Isolation
Product group Antibodies
ReactivityHuman
Overview
- SupplierGeneTex
- Product NameLaminin 511 antibody [12D]
- Delivery Days Customer9
- Antibody SpecificityThis antibody specifically interacts with the trimeric structure of laminin-511 isoform but does not react with any of the alpha 5, beta 1 and gamma 1 chains in the reducing conditions. Furthermore, it has been validated that clone 12D does not react with
- Application Supplier NoteWB: 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Purification/Extraction/Isolation
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID12D
- ConjugateUnconjugated
- FormulationLiquid
- HostMouse
- IsotypeIgG2b
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Angiomodulin, a marker of cancer vasculature, is upregulated by vascular endothelial growth factor and increases vascular permeability as a ligand of integrin alphavbeta3. Komiya E et al., 2014 Jun, Cancer MedRead more