LAMTOR4 antibody

GeneTex

LAMTOR4 antibody

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

0.44 mg/ml

Unconjugated

LAMTOR4

late endosomal/lysosomal adaptor, MAPK and MTOR activator 4

C7orf59; late endosomal/lysosomal adaptor and MAPK and MTOR activator 4; ragulator complex protein LAMTOR4; UPF0539 protein C7orf59

Rabbit

IgG

Ragulator complex protein LAMTOR4

As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated.1 Publication

Human

-20°C or -80°C,2°C to 8°C

12352203