Lanraplenib

MedChem Express

Lanraplenib [1800046-95-0]

10

1800046-95-0

Research Use Only

99.12

C23H25N9O

443.50

Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor ( IC 50 =9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib (GS-9876) inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans [1] [2] [3] .

NC1=CN=CC(C2=CN3C(C(NC4=CC=C(N5CCN(C6COC6)CC5)C=C4)=N2)=NC=C3)=N1

-20°C,2°C to 8°C

12352200