Lapatinib-d4 (tosylate) [2749856-05-9]

MedChem Express

Lapatinib-d4 (tosylate) [2749856-05-9]

5

CHEMICAL,detergents_surfactants

Research Use Only

C36H30D4ClFN4O7S2

757.28

Lapatinib-d4 (GW572016-d4) tosylate is deuterium labeled Lapatinib (tosylate). Lapatinib (GW572016) tosylate is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively[1][2].

O=S(O)(C1=CC=C(C=C1)C)=O.CS(C([2H])([2H])C([2H])([2H])NCC2=CC=C(O2)C3=CC(C(NC4=CC(Cl)=C(C=C4)OCC5=CC(F)=CC=C5)=NC=N6)=C6C=C3)(=O)=O

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