Lapatinib (ditosylate monohydrate)

MedChem Express

Lapatinib (ditosylate monohydrate) [388082-78-8]

10

388082-78-8

Research Use Only

99.93

C43H44ClFN4O11S3

943.48

Lapatinib ditosylate monohydrate (GW572016 ditosylate monohydrate) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC 50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively [1] .

O=S(CCNCC1=CC=C(C2=CC3=C(NC4=CC=C(OCC5=CC=CC(F)=C5)C(Cl)=C4)N=CN=C3C=C2)O1)(C)=O.O=S(C6=CC=C(C)C=C6)(O)=O.O=S(C7=CC=C(C)C=C7)(O)=O.O

2°C to 8°C

12352200