Lapatinib Ditosylate
T6235
CAS Number388082-77-7
Product group Chemicals
Molecular Weight925.46
Overview
- SupplierTargetMol Chemicals
- Product NameLapatinib Ditosylate
- Delivery Days Customer4
- CAS Number388082-77-7
- Category SupplierChemical
- Chemical NameLapatinib Ditosylate
- Molecular FormulaC29H26ClFN4O4S·2C7H8O3S
- Molecular Weight925.46
- Scientific DescriptionLapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).
- Shelf life instruction3 years
- SMILESCc1ccc(cc1)S(O)(=O)=O.Cc1ccc(cc1)S(O)(=O)=O.CS(=O)(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1
- Storage Instruction-20°
- UNSPSC12352200
References
- Wainberg ZA, et al. Lapatinib, a dual EGFR and HER2 kinase inhibitor, selectively inhibits HER2-amplified human gastric cancer cells and is synergistic with trastuzumab in vitro and in vivo. Clin Cancer Res. 2010 Mar 1;16(5):1509-19.