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WB analysis of RAW264.7 cell lysates using GTX87286 LARG antibody. The lane on the right is blocked with the synthesized peptide.
WB analysis of RAW264.7 cell lysates using GTX87286 LARG antibody. The lane on the right is blocked with the synthesized peptide.
WB analysis of RAW264.7 cell lysates using GTX87286 LARG antibody. The lane on the right is blocked with the synthesized peptide.

LARG antibody

GTX87286
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityMouse
TargetARHGEF12
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Overview

  • Supplier
    GeneTex
  • Product Name
    LARG antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500~1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID23365
  • Target name
    ARHGEF12
  • Target description
    Rho guanine nucleotide exchange factor 12
  • Target synonyms
    LARG; leukemia-associated rho guanine nucleotide exchange factor; leukemia-associated RhoGEF; PRO2792; Rho guanine nucleotide exchange factor (GEF) 12; rho guanine nucleotide exchange factor 12
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9NZN5
  • Protein Name
    Rho guanine nucleotide exchange factor 12
  • Scientific Description
    Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
  • Reactivity
    Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Rho GTPase activity crosstalk mediated by Arhgef11 and Arhgef12 coordinates cell protrusion-retraction cycles.
    Read more