
WB analysis of RAW264.7 cell lysates using GTX87286 LARG antibody. The lane on the right is blocked with the synthesized peptide.
LARG antibody
GTX87286
Overview
- SupplierGeneTex
- Product NameLARG antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500~1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID23365
- Target nameARHGEF12
- Target descriptionRho guanine nucleotide exchange factor 12
- Target synonymsLARG; leukemia-associated rho guanine nucleotide exchange factor; leukemia-associated RhoGEF; PRO2792; Rho guanine nucleotide exchange factor (GEF) 12; rho guanine nucleotide exchange factor 12
- HostRabbit
- IsotypeIgG
- Protein IDQ9NZN5
- Protein NameRho guanine nucleotide exchange factor 12
- Scientific DescriptionRho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
- ReactivityMouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Rho GTPase activity crosstalk mediated by Arhgef11 and Arhgef12 coordinates cell protrusion-retraction cycles.Read more