Lasiocarpine [303-34-4]

MedChem Express

Lasiocarpine [303-34-4]

10

303-34-4

Research Use Only

C21H33NO7

411.49

Lasiocarpine, a hepatotoxic pyrrolizidine alkaloid (PA), causes fatal liver veno-occlusive disease in vivo. Lasiocarpine is toxic only after its metabolic conversion to the toxic intermediate, including dehydrolasiocarpine and N-oxide[1].

CO[C@H](C)[C@](C(C)(O)C)(O)C(OCC1=CCN2[C@@]1([H])[C@@H](OC(/C(C)=C\C)=O)CC2)=O

12352200