LAT blocking peptide

GeneTex

LAT blocking peptide

9

Research Use Only

LAT

linker for activation of T cells

IMD52, LAT1, pp36, linker for activation of T-cells family member 1, 36 kDa phospho-tyrosine adapter protein, 36 kDa phospho-tyrosine adaptor protein, 36 kDa phosphotyrosine adapter protein, linker for activation of T cells, transmembrane adaptor, p36-38

The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

41116100

Human