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(-)-Latifolin [10154-42-4]

HY-N8380
MedChem Express
CAS Number10154-42-4
Product group Chemicals
Molecular Weight286.32
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Overview

  • Supplier
    MedChem Express
  • Product Name
    (-)-Latifolin [10154-42-4]
  • Delivery Days Customer
    5
  • CAS Number
    10154-42-4
  • Certification
    Research Use Only
  • Molecular Formula
    C17H18O4
  • Molecular Weight
    286.32
  • Scientific Description
    (-)-Latifolin, a flavonoid, induces apoptotic cell death by targeting PI3K/AKT/mTOR/p70S6K signaling. (-)-Latifolin significantly inhibits the cell proliferation of oral squamous cell carcinoma (OSCC), and causes the anti-metastatic activities by effectively blocking cell migration, invasion, and adhesion via the inactivation of FAK/Src. (-)-Latifolin suppresses autophagic-related proteins and autophagosome formation. (-)-Latifolin inhibits necroptosis by dephosphorylating necroptosis-regulatory proteins (RIP1, RIP3, and MLKL). (-)-Latifolin has beneficial effects on anti-aging, anti-carcinogenic, anti-inflammatory, and cardio-protective activities[1].
  • SMILES
    OC1=CC([C@@H](C2=CC=CC=C2O)C=C)=C(OC)C=C1OC
  • UNSPSC
    12352200

MSDS

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