
Chemical Structure
Latrunculin A [76343-93-6]

AG-CN2-0027
Overview
- SupplierAdipoGen Life Sciences
- Product NameLatrunculin A
- Delivery Days Customer10
- CAS Number76343-93-6
- CertificationResearch Use Only
- Estimated Purity>97%
- Hazard InformationWarning
- Molecular FormulaC22H31NO5S
- Molecular Weight421.6
- Scientific DescriptionCell permeable marine toxin [1]. Disrupts microfilament-mediated processes [2]. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin [1, 2, 3, 6]. Depolymerizes actin filaments (F-actin) [3]. Potent phagocytosis inhibitor [4]. Anticancer compound [7, 8]. Suppresses hypoxia-induced HIF-1 activation in tumor cells [7]. Inhibits tumor cell invasion [7]. Acts via a different mechanism than cytochalasins. - Chemical. CAS: 76343-93-6. Formula: C22H31NO5S. MW: 421.6. Isolated from Latrunculia magnifica. Cell permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Depolymerizes actin filaments (F-actin). Potent phagocytosis inhibitor. Anticancer compound. Suppresses hypoxia-induced HIF-1 activation in tumor cells. Inhibits tumor cell invasion. Acts via a different mechanism than cytochalasins.
- SMILESO=C(SC1)N[C@]1([H])[C@](C2)(O)O[C@@H](C[C@H]2O3)CC[C@H](C)/C=C\C=C\CC/C(C)=C\C3=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200