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ICC/IF analysis of HepG2 cells using GTX87529 LATS2 antibody. The picture on the right is blocked with the synthesized peptide.
ICC/IF analysis of HepG2 cells using GTX87529 LATS2 antibody. The picture on the right is blocked with the synthesized peptide.
ICC/IF analysis of HepG2 cells using GTX87529 LATS2 antibody. The picture on the right is blocked with the synthesized peptide.

LATS2 antibody

GTX87529
GeneTex
ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetLATS2
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Overview

  • Supplier
    GeneTex
  • Product Name
    LATS2 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    ICC/IF: 1:100~1:500. IHC-P: 1:50~1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID26524
  • Target name
    LATS2
  • Target description
    large tumor suppressor kinase 2
  • Target synonyms
    kinase phosphorylated during mitosis protein; KPM; large tumor suppressor homolog 2; LATS (large tumor suppressor, Drosophila) homolog 2; LATS, large tumor suppressor, homolog 2; serine/threonine kinase KPM; serine/threonine-protein kinase kpm; serine/threonine-protein kinase LATS2; warts-like kinase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9NRM7
  • Protein Name
    Serine/threonine-protein kinase LATS2
  • Scientific Description
    This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Sophoridine inhibits lung cancer cell growth and enhances cisplatin sensitivity through activation of the p53 and Hippo signaling pathways. Zhu L et al., 2020 Jun 5, Gene
    Read more
  • Furry protein suppresses nuclear localization of yes-associated protein (YAP) by activating NDR kinase and binding to YAP. Irie K et al., 2020 Mar 6, J Biol Chem
    Read more