LC kinetic stabilizer-1 [2495750-19-9]

MedChem Express

LC kinetic stabilizer-1 [2495750-19-9]

10

2495750-19-9

Research Use Only

C27H31N5O3

473.57

LC kinetic stabilizer-1 (compound 21) is a potent and selective amyloidogenic immunoglobulin light chain kinetic stabilizer with EC50s of 140 and 74.1 nM for WIL-FL* and WIL-FL* T46L/F49Y, respectively. WIL-FL is an amyloidogenic FL LC dimer[1].

O=C1OC2=CC(N(CC)CC)=CC=C2C(C)=C1CCNC(NCC3=CC(C4=CNC=N4)=CC=C3)=O

12131703