Bio-Connect

LC-MB12

HY-149843
MedChem Express
Estimated Purity99.23
Product group Chemicals
Molecular Weight899.78
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Overview

  • Supplier
    MedChem Express
  • Product Name
    LC-MB12 [2828438-38-4]
  • Delivery Days Customer
    14
  • Certification
    Research Use Only
  • Estimated Purity
    99.23
  • Molecular Formula
    C43H44Cl2N10O8
  • Molecular Weight
    899.78
  • Scientific Description
    LC-MB12 is an orally active PROTAC compound targets FGFR2 degradation with a DC50 of 11.8 nM. LC-MB12 contains BGJ398 (a FGFR2 inhibitor), PROTAC linker and CRBN.LC-MB12 inhibits FGFR2 signaling in gastric cancer cells and has anti-tumor activity[1].
  • SMILES
    O=C(N(C)C1=CC(NC2=CC=C(N3CCN(CC3)C(C4CCN(CC4)C5=CC=C6C(N(C7C(NC(CC7)=O)=O)C(C6=C5)=O)=O)=O)C=C2)=NC=N1)NC8=C(Cl)C(OC)=CC(OC)=C8Cl
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12131703