LDC0496 [2411874-83-2]

MedChem Express

LDC0496 [2411874-83-2]

10

2411874-83-2

Research Use Only

C32H35N5O3

537.65

LDC0496 is a potent and selective EGFR inhibitor. LDC0496 possesses intense inhibitory potency toward EGFR and Her2 exon20 insertion mutations, as well as selectivity over wild type EGFR and within the kinome[1].

CC(C=CC(C1=C(NC2=NC=C(C=C21)C(OC(C)C)=O)C3=CC=C(C=C3)N4CCN(CC4)C)=C5)=C5NC(C=C)=O

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