LDHA/PDKs-IN-1 [2490699-40-4]
HY-146977
Overview
- SupplierMedChem Express
- Product NameLDHA/PDKs-IN-1 [2490699-40-4]
- Delivery Days Customer10
- CAS Number2490699-40-4
- CertificationResearch Use Only
- Molecular FormulaC19H21FN2O4
- Molecular Weight360.38
- Scientific DescriptionLDHA/PDKs-IN-1 (compound 20e) is a potent and dual inhibitor of PDKs and LDHA with IC50s of 0.8 and 0.15 microM, respectively. LDHA/PDKs-IN-1 reduces A549 cell proliferation with an EC50 of 13.2 microM and decreases the lactate formation, and increases oxygen consumption. LDHA/PDKs-IN-1 has the potential for the research of cancer diseases[1].
- SMILESCC1=C(C(C=CO1)=O)OCCN2CCN(CC2)C(C3=CC=C(C=C3)F)=O
- UNSPSC12131703