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LDN-193189

S2618
Selleck Chemicals
CAS Number1062368-24-4
Product group Chemicals
Estimated Purity...
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    LDN-193189 [1062368-24-4]
  • Delivery Days Customer
    9
  • CAS Number
    1062368-24-4
  • Certification
    Research Use Only
  • Estimated Purity
    ...
  • Scientific Description
    LDN-193189 (DM3189) is a selective BMP signaling inhibitor, inhibits the ALK1, ALK2, ALK3 and ALK6 with IC50s of 0.8 nM, 0.8 nM, 5.3 nM and 16.7 nM in the kinase assay, respectively. LDN-193189 inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50s of 5 nM and 30 nM in C2C12 cells, respectively, exhibits 200-fold selectivity for BMP versus TGF-beta. For cell testing, the water-soluble S7507 LDN-193189 2HCl is recommended.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!
  • Storage Instruction
    -80°C
  • UNSPSC
    51202000