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ProductsBack/LDN-214117 [1627503-67-6]

LDN-214117 [1627503-67-6]

Research Use Only
HY-16712
MedChem Express
CAS Number1627503-67-6
DownloadMSDS
Product group Chemicals
Estimated Purity99.92
Molecular Weight419.52
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Overview

  • Supplier
    MedChem Express
  • Product Name
    LDN-214117 [1627503-67-6]
  • Delivery Days Customer
    10
  • CAS Number
    1627503-67-6
  • Certification
    Research Use Only
  • Estimated Purity
    99.92
  • Molecular Formula
    C25H29N3O3
  • Molecular Weight
    419.52
  • Scientific Description
    LDN-214117 is an orally active ALK2 inhibitor with well-tolerated and good brain penetration. LDN-214117 has a high selectivity and low cytotoxicity for ALK2 with an IC50 value of 24 nM. LDN-214117 also is a specific bone morphogenetic proteins (BMPs) signaling inhibitor and has relatively selective inhibition for BMP6 with an IC50 value of 100 nM. LDN-214117 can be used for the research of fibrodysplasia ossificans progressiva (FOP), diffuse intrinsic pontine glioma (DIPG) [1][2].
  • SMILES
    CC(C(C1=CC(OC)=C(OC)C(OC)=C1)=C2)=NC=C2C3=CC=C(N4CCNCC4)C=C3
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200