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LDN-57444 [668467-91-2]

27706
BPS Bioscience
CAS Number668467-91-2
Product group Chemicals
Estimated Purity≥98%
Molecular Weight397.6 Da
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Overview

  • Supplier
    BPS Bioscience
  • Product Name
    LDN-57444
  • Delivery Days Customer
    7
  • CAS Number
    668467-91-2
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Molecular Formula
    C17H11Cl3N2O3
  • Molecular Weight
    397.6 Da
  • Scientific Description
    LDN-57444 is a cell permeable ubiquitin C-terminal hydrolase (UCH-L1) inhibitor (Ki=0.4 microM). Decreases proteasome activity and increases levels of ubiquitinated proteins. Induces apoptosis and causes dramatic alterations in synaptic protein distribution and spine morphology in vivo. LDN-57444 is a useful tool to study UCH-L1 in different pathological conditions such as cancer and neurodegeneration.
  • UNSPSC
    51202000

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