Ledipasvir

MedChem Express

Ledipasvir [1256388-51-8]

10

1256388-51-8

Research Use Only

99.68

C49H54F2N8O6

889.00

Ledipasvir (GS-5885) is an inhibitor of the hepatitis C virus NS5A , with EC 50 s of 34 pM and 4 pM against genotype 1a and 1b replicon, respectively. Ledipasvir is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 1.62 microM [3] .

O=C(OC)N[C@H](C(N([C@H](C1=NC=C(C2=CC(C(F)(F)C3=C4C=CC(C5=CC=C6N=C([C@H]7N(C([C@@H](NC(OC)=O)C(C)C)=O)[C@]8([H])CC[C@@]7([H])C8)NC6=C5)=C3)=C4C=C2)N1)C9)CC%109CC%10)=O)C(C)C

-20°C,2°C to 8°C

12352200