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Leelamine [1446-61-3]

HY-W005629
MedChem Express
CAS Number1446-61-3
Product group Chemicals
Estimated Purity98.36
Molecular Weight285.48
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Leelamine [1446-61-3]
  • Delivery Days Customer
    10
  • CAS Number
    1446-61-3
  • Certification
    Research Use Only
  • Estimated Purity
    98.36
  • Molecular Formula
    C20H31N
  • Molecular Weight
    285.48
  • Scientific Description
    Leelamine is an orally active pyruvate dehydrogenase kinase (PDK) inhibitor with an IC50 value of 9.5 microM, showing a blood glucose lowering effect in the diabetic mouse. Leelamine is also a weak agonist of cannabinoid receptors CB1 and CB2. Leelamine decreases mitotic activity, prostate-specific antigen expression and induces Apoptosis to cell death in cancer cells[1][2][3].
  • SMILES
    NC[C@]1(C)CCC[C@]2(C)C3=C(CC[C@@]12[H])C=C(C(C)C)C=C3
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200