LEI105 [1800327-36-9]
HY-112828
CAS Number1800327-36-9
Product group Chemicals
Molecular Weight384.47
Overview
- SupplierMedChem Express
- Product NameLEI105 [1800327-36-9]
- Delivery Days Customer9
- CAS Number1800327-36-9
- CertificationResearch Use Only
- Molecular FormulaC25H24N2O2
- Molecular Weight384.47
- Scientific DescriptionLEI105 is a potent, highly selective and reversible dual diacylglycerol lipase (DAGL)-alpha/DAGL-beta inhibitor. LEI105 reduces 2-arachidonoylglycerol levels in Neuro2A cells. LEI105 also reduces cannabinoid CB1-receptor-mediated short-term synaptic plasticity in a mouse hippocampal slice model. LEI105 is promising for research of diseases, such as obesity, related metabolic disorders and neuroinflammation[1].
- SMILESO=C(C1=NC2=NC=C(C3=CC=C(C)C=C3)C=C2O1)CCCCCC4=CC=CC=C4
- UNSPSC12352200