Lenalidomide

MedChem Express

Lenalidomide [191732-72-6]

10

191732-72-6

Research Use Only

99.98

C13H13N3O3

259.26

Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN) , and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells [1] [2] .

O=C1C2=CC=CC(N)=C2CN1C(C(N3)=O)CCC3=O

-20°C,2°C to 8°C

12352200