Lenalidomide 4-alkyl-C3-azide [2399455-71-9]
HY-161131
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product NameLenalidomide 4-alkyl-C3-azide [2399455-71-9]
- Delivery Days Customer14
- CAS Number2399455-71-9
- CertificationResearch Use Only
- Molecular FormulaC16H18N6O3
- Molecular Weight342.35
- Scientific DescriptionLenalidomide 4-alkyl-C3-azide (compound 4a) is a click chemical modified Lenalidomide (HY-A0003) that can be used to synthesize PROTACs. Lenalidomide is an orally active immunomodulator and a ligand for the ubiquitin E3 ligase cereblon (CRBN). Lenalidomide 4-alkyl-C3-azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition reactions (SPAAC) can also occur with molecules containing DBCO or BCN groups[1].
- SMILES[N-]=[N+]=NCCCNC1=CC=CC2=C1CN(C3C(NC(CC3)=O)=O)C2=O
- UNSPSC41115800