Lenalidomide-C4-NH2 (hydrochloride)
HY-115446A
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product NameLenalidomide-C4-NH2 (hydrochloride)
- Delivery Days Customer10
- CertificationResearch Use Only
- Estimated Purity98.85
- Molecular FormulaC17H22ClN3O3
- Molecular Weight351.83
- Scientific DescriptionLenalidomide-C4-NH2 hydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C4-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC (Compound 24), which has IC50s of 0.98 nM and 13.7 nM in inhibition of RS4;11 and MOLM-13 acute leukemia cell lines growth, respectively[1].
- SMILESO=C(C(N(CC1=C2C=CC=C1CCCCN)C2=O)CC3)NC3=O.Cl
- Storage Instruction2°C to 8°C
- UNSPSC41115800