Lenalidomide-C9-aldehyde

TargetMol Chemicals

Lenalidomide-C9-aldehyde

16

Chemical

Research Use Only

Lenalidomide-C9-aldehyde

C23H30N2O4

398.5

Lenalidomide-C9-aldehyde is a synthesized E3 ligase ligand-linker conjugate that incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide-C9-aldehyde can be used in the synthesis of a series of PROTACs, such as INY-03-041. INY-03-041 is a potent, highly selective and PROTAC-based pan-Akt degrader. INY-03-041 inhibits Akt1, Akt2 and Akt3 with IC50s of 2.0 nM, 6.8 nM and 3.5 nM, respectively[1].

3 years

O=C(C(N(CC1=C2C=CC=C1CCCCCCCCCC=O)C2=O)CC3)NC3=O

-20°C

12352200