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Lenalidomide (hemihydrate) [847871-99-2]

HY-A0003B
MedChem Express
CAS Number847871-99-2
Product group Chemicals
Estimated Purity99.98
Molecular Weight268.27
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Lenalidomide (hemihydrate) [847871-99-2]
  • Delivery Days Customer
    10
  • CAS Number
    847871-99-2
  • Certification
    Research Use Only
  • Estimated Purity
    99.98
  • Molecular Formula
    C13H14N3O3.5
  • Molecular Weight
    268.27
  • Scientific Description
    Lenalidomide hemihydrate (CC-5013 hemihydrate), a derivative of Thalidomide, acts as molecular glue. Lenalidomide hemihydrate is an orally active immunomodulator. Lenalidomide hemihydrate (CC-5013 hemihydrate) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide hemihydrate (CC-5013 hemihydrate) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells[1][2].
  • SMILES
    O=C1N(C2C(NC(CC2)=O)=O)CC3=C(N)C=CC=C31.[0.5 H2O]
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200