Lenalidomide (hemihydrate) [847871-99-2]
HY-A0003B
CAS Number847871-99-2
Product group Chemicals
Estimated Purity99.98
Molecular Weight268.27
Overview
- SupplierMedChem Express
- Product NameLenalidomide (hemihydrate) [847871-99-2]
- Delivery Days Customer10
- CAS Number847871-99-2
- CertificationResearch Use Only
- Estimated Purity99.98
- Molecular FormulaC13H14N3O3.5
- Molecular Weight268.27
- Scientific DescriptionLenalidomide hemihydrate (CC-5013 hemihydrate), a derivative of Thalidomide, acts as molecular glue. Lenalidomide hemihydrate is an orally active immunomodulator. Lenalidomide hemihydrate (CC-5013 hemihydrate) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide hemihydrate (CC-5013 hemihydrate) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells[1][2].
- SMILESO=C1N(C2C(NC(CC2)=O)=O)CC3=C(N)C=CC=C31.[0.5 H2O]
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
![Lenalidomide hemihydrate [847871-99-2]](https://www.targetmol.com/group3/M00/03/56/CgoaEWY7SHCESSI2AAAAAGu1u0E993.png)