Lenalidomide-PEG1-azide [2185795-67-7]
HY-133139
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product NameLenalidomide-PEG1-azide [2185795-67-7]
- Delivery Days Customer10
- CAS Number2185795-67-7
- CertificationResearch Use Only
- Estimated Purity95.84
- Molecular FormulaC17H18N6O5
- Molecular Weight386.36
- Scientific DescriptionLenalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Lenalidomide-PEG1-azide incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-2 (HY-133136)[1]. Lenalidomide-PEG1-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- SMILESO=C(NC1=CC=CC2=C1CN(C(CC3)C(NC3=O)=O)C2=O)COCCN=[N+]=[N-]
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41115800